Keeley spent his first three years of his career in
New Orleans, where he taught at
Louisiana State University and was a visiting surgeon at
Charity Hospital from 1938 until 1941. In 1941, Keeley joined the faculty of the Loyola University Stritch School of Medicine as an assistant clinical professor. The cardinal, who had been battling a blood clot and had to have his arm amputated, honored Keeley in May 1958 by conferring upon him the pontifical order, the Knight of St. Gregory. From 1954 until 1958, Keeley was assistant chairman of the department of surgery at Stritch. From 1958 until 1969, Keeley was chairman of the department of surgery at Stritch. He also was appointed in 1969 to be head of surgery at Chicago’s Mercy Hospital, where he pioneered the development of cardiovascular surgery. In 1965, Keeley tended to Cardinal
Albert Gregory Meyer in Chicago after the 61-year-old prelate was hospitalized with an apparent gall bladder disorder. Keeley cared for Meyer when he underwent brain surgery and afterward, until Meyer's death on April 9, 1965. In 1966,
Archbishop of Chicago John Cody, then the head of Chicago’s Roman Catholic archdiocese, named Keeley to be one of the members of a new commission on human relations and ecumenism. In 1976, Keeley received the Stritch Medal from Loyola University, which is presented annually to a physician or medical researcher who exhibits “to a high degree professional competence, resourcefulness, loyalty, benevolence and dedication.” Keeley specialized in thoracic and vascular pediatric surgery and the study of blood volumes. == Personal life ==