Low induced the Mahratta
Peshwa,
Baji Rao II, to place himself under British protection. When Baji Rao retired to
Bithoor, near
Kanpur, Low was appointed Resident there. He filled the post for six years. From that time Low's services were mostly political, though at
Lucknow and later at
Hyderabad his functions included the control of troops. In 1825 he became political agent at
Jeypore. In 1830 he was appointed by
Lord William Bentinck to a similar post in
Gwalior State, where he opposed the regent
Baiza Bai. In 1831 he was sent as Resident to Lucknow. In 1837 the
East India Company took over the government of
Oudh State. Low suggested the alternative of deposing the king and placing the heir-apparent on the throne, and the governor-general
Lord Auckland left the matter to Low. Meanwhile, the king died suddenly; a pretender and court favourite was placed on the throne and the heir was taken prisoner. Summoning a Bengal regiment to his aid, Low, after a parley, had the gates of the palace blown open and the pretender seized. The heir was then installed by the British resident. Low was made
CB on 20 July 1838. He made efforts to suppress a
taluqdar,
Bhagwant Singh, in 1841. In poor health, he returned to the United Kingdom in 1842. Low returned to India in 1847, and in 1848 was appointed the governor-general's agent in
Rajputana and commissioner at
Ajmer-Merwara. There he remained until 1852, when he was sent by
Lord Dalhousie to Hyderabad, in succession to
James Stuart Fraser, as resident with the Nizam. There he negotiated the treaty by which the
Berar Division was assigned to the British government, in return for the maintenance of the Hyderabad subsidiary force. On 22 September 1853 Low was appointed a member of council. His experience of Indian princes was wide, but had not made him a hawk. In February 1854, he protested the
Nagpur annexation; on this, and on other occasions, his views were ignored by Dalhousie. In the questions that ended with the annexation of Awadh, Low advocated interference in 1855. When early in May 1857 news presaging the
Indian Rebellion, Low at first advised leniency; but the outbreaks at
Meerut and
Delhi saw him advocate the recovery of Delhi. ==Last years==