Gulland played a pivotal role in some of the research which led to the decoding of DNA by Watson and Crick in 1953. The Nottingham team, which included his colleagues
Denis Jordan, Cedric Threlfall, and
Michael Creeth, produced three papers in 1947: one led to high quality non-degraded DNA samples extracted without using acids or alkalis, the next measured the viscosity of DNA and the third proved the all-important hydrogen bond structures within it. Five years later Watson dismissed the Nottingham team’s work incorrectly, and it took a year for him to realise his mistake. Eventually however "...a rereading of J. M. Gulland's and D. O. Jordan's papers...made me finally realize the strength of their conclusion that a large fraction, if not all, of the bases formed hydrogen bonds to other bases." Once Watson had recognised the key role of the hydrogen bonds then the decoding of DNA seems to have come within about a week or ten days. The Nottingham team’s work was also acknowledged in the first papers concerning the decoding of DNA by
Rosalind Franklin and
Raymond Gosling who reported that "Gulland and his collaborators … showed that … CO and NH2 groups of the bases are inaccessible … whereas the phosphate groups are fully accessible." Following these early citations rather less attention was given to the significance of the work of Gulland and his colleagues. By the time of the DNA decoding in 1953 events had moved on with the break-up of the Nottingham team: Gulland had moved on to become Research Director at the Institute of Brewing shortly before his untimely death in 1947, whilst Jordan and Creeth were both working outside the UK. However commemorations in 2010 and 2017 at the University of Nottingham posthumously acknowledged all their contributions, as did
The Annotated and Illustrated Double Helix (2012). There has been some speculative debate as to whether, if these events had turned out differently, the Nottingham team might have gone on to make the DNA decoding discovery themselves. ==Family==