Canada •
John F. Mitchell (1862–1943), Conservative member of the Legislative Assembly of Manitoba (1907–10), alderman and acting mayor (1900) of Winnipeg, Manitoba •
John William Mitchell (1872–1952), mayor (1911–13) and alderman (1905–11, 1915) of Calgary, Alberta •
John Henry Mitchell, Canadian politician,
Liberal-Progressive member of the Legislative Assembly of Ontario (1926–29) •
John Mitchell (Ontario politician), first president and de facto leader of the Ontario Co-operative Commonwealth Federation (1934–1941), alderman of Hamilton, Ontario
United Kingdom •
John Mitchell (MP for City of London) (d. 1445), a member of the medieval
Parliament of England (numerous parliaments between 1411 and 1435) •
John Mitchell (MP for Truro), a member of the Tudor period
Parliament of England (the Parliament of 1563–1567) •
John Mitchell (Hull politician) (c. 1781–1859), Member of Parliament for Kingston-upon-Hull (1818–26) •
John Mitchel (1815–1875), Irish nationalist journalist and politician, Member of Parliament for
County Tipperary (1875) •
John Thomas Whitehead Mitchell (1828–1895), British co-operative activist who served as president of the 1879 and 1892 Co-operative Congress
United States •
John Mitchell (Pennsylvania politician) (1781–1849), United States Congressman from Pennsylvania •
John Mitchell (United Mine Workers) (1870–1919), labor leader •
John Mitchell Jr. (politician) or "Larry" (born 1954), American politician and member of the Delaware House of Representatives •
John H. Mitchell (1835–1905), American politician and senator from Oregon •
John H. Mitchell (Iowa politician) (1899–1992), Iowa state representative and attorney general •
John I. Mitchell (1838–1907), United States Senator from Pennsylvania •
John Joseph Mitchell (1873–1925), United States Representative from Massachusetts •
John L. Mitchell (1842–1904), American politician from Wisconsin and father of Gen. Billy Mitchell •
John M. Mitchell (1858–1905), United States Representative from New York •
John N. Mitchell (1913–1988), United States Attorney General and Nixon Watergate conspirator •
John Purroy Mitchel (1879–1918), mayor of New York •
John Ridley Mitchell (1877–1962), United States Representative from Tennessee
Other countries •
John Mitchell (Australian politician) (1869–1943), member of the Victorian Parliament •
John Walker Mitchell (1832–1914), Scottish-born New Zealand politician ==Science==