He was the son of the Rev. Mark Nicholson of
Barbados, the eldest in a family of six and born there; his mother was Lucy Reynold Ellcock. He matriculated at
The Queen's College, Oxford in 1825, at age 16, graduating B.A. in 1830. He then went to the
University of Göttingen to study under
Heinrich Ewald.
Ludwig Leichhardt, a friend there, mentioned that Nicholson left Göttingen around the end of 1833. Nicholson's translation of Ewald's
Hebrew Grammar was published by 1835. In 1838 the Rev. Mark Nicholson died: to this point he had supported John Nicholson and his brother William with generous allowances. William had returned to the family home at
Clifton, Bristol, and Leichhardt visited him there. Nicholson entered the
University of Tübingen in 1838. He was awarded a doctorate there for a translation from the Arabic. Nicholson then returned to England, settling at
Penrith, Cumberland. The
Maronite scholar
Ahmad Faris al-Shidyaq paid an extended visit to him there, in winter 1851–2, examining manuscripts in Arabic. Another visitor, and a long-term correspondent, was
Francis William Newman. The
Swedenborgian traveller Rudolph Leonhard Tafel encountered there
Mark Nicholson, John's youngest brother, in 1857. In 1854, Nicholson was one of the founders of the Penrith Working Men's Reading Room, with
Lord Brougham and
William Marshall. ==Works==