In 1801 Pickering returned to the United States in 1801 and settled again in Salem with his paternal uncle. There he studied law ("read the law") in the office of Samuel Putnam, who was married to one of Pickering's cousins. He was admitted to the bar in 1804. At the time Pickering was still residing with his unmarried uncle, a widowed aunt, and a second cousin, Sarah White. Pickering and White formed a friendship. On March 3, 1805, Pickering and White married in a ceremony held in the parlor of the
Pickering Mansion. The couple moved to a home on
Chestnut Street in Salem. Later that year, their daughter, Mary Orne Pickering, was born. Their eldest son, John Pickering Jr., was born on November 8, 1808. Their final child,
Henry White Pickering, was born on May 27, 1811. ==Academic works==