He acquired such a reputation as a reformist Catholic preacher that in 1543, after the arrest of
Cardinal Beaton,
the regent Arran procured a dispensation for him to leave the monastery so that he might become one of his chaplains. The entry in the treasurer's accounts for February 1543 of payment for a gown, doublet, hose, and bonnet for him as chaplain of the lord-governor, probably indicates the date when he first entered upon his duties. At their request the governor allowed him and Thomas Gwilliam (or Williams) to preach publicly against current errors and abuses. Both were very effective. Rough, although according to Knox ‘not so learned’ as Williams, was ‘yet more simple and vehement against all impiety’ The preaching roused the special indignation of the Franciscans, who, according to Knox, ‘rouped as they had been ravens, yea, rather they yelled like devils in hell “heresy ! heresy ! Gwilliam and Rough will carry the governor to the devil”’. On account of the advice, as is supposed, of
John Hamilton, Abbot of Arbroath, and
David Panter (afterwards
bishop of Ross), who had arrived from France, they were both prohibited from preaching; and Rough took refuge in the wild districts of
Kyle in Ayrshire, where he remained until after the murder of Cardinal Beaton in 1546. By this date he had broken completely with Catholicism. After the murder, Rough came to St. Andrews, and, besides acting as chaplain to the garrison in the castle, began to preach in the parish church. Here he met
John Knox, whom in a sermon he publicly exhorted to undertake the office of a preacher; and Knox, who had been a disciple of
George Wishart, and who at this time had brought the aid of his vigorous pen to the support of the teaching of Rough in opposition to Dean Annand of St. Andrews, was at last induced to preach in the parish church his first sermon against the ‘corruptions of the Papistry’. Knox's irregular call was approved by the congregation. Knox and Rough were soon summoned before
John Winram, the Catholic vicar-general of St. Andrews, but their defence was conducted by Knox with such skill as completely to confound their adversaries. ==In England==