The center was originated by UCLA scientists and volunteers who began working together in the late 1960s. The center was formally established in 1974 and was designated as a
comprehensive cancer center by the
National Cancer Institute in 1976. The namesake of the center is the Jonsson family; entrepreneur and philanthropist Kenneth Alan Jonsson (the son of
Texas Instruments co-founder
J. Erik Jonsson), along with his wife Diana Gordon Jonsson, made a $1 million gift for UCLA in 1975 to establish the center, and continued to financially support the center over a period of decades.
Joseph W. Cullen served as a deputy director of the center. ==Organization, activities, and funding==