Wicks was selected by the
Chicago Cubs in the first round with the 21st overall selection of the
2021 Major League Baseball draft. This makes Wicks both the highest and the first ever first round draft pick to come out of Kansas State's baseball program. He signed for a $3.1 million
signing bonus. Wicks made his professional debut with the
South Bend Cubs of the
High-A Central, pitching seven innings while giving up four earned runs and three walks while striking out five. He returned to South Bend to open the 2022 season. In mid-July, he was promoted to the
Tennessee Smokies of the
Double-A Southern League. Over 24 starts between the two teams, he went 4-6 with a 3.80 ERA and 121 strikeouts over innings. He returned to the Smokies open the 2023 season. In late June, he was promoted to the
Iowa Cubs of the
Triple-A International League. Across 20 starts between the teams, he went 7-0 with a 3.55 ERA and 99 strikeouts in innings. On August 26, 2023, Wicks was promoted to the major leagues by the Cubs to make his first career start against the
Pittsburgh Pirates. He made his MLB debut that day at
PNC Park and allowed one run on two hits and one walk while recording nine strikeouts in a 10-6 Cubs victory. Across seven starts with the Cubs, Wicks compiled a 4–1 record and 4.41 ERA with 24 strikeouts over innings pitched. Wicks was named to his first
Opening Day roster to begin the 2024 season as a member of Chicago's starting rotation. He was placed on the injured list with a Grade 2 oblique strain on June 15, and was transferred to the 60–day injured list on July 19. Wicks was activated on September 1. Across ten starts for the Cubs, Wicks compiled a 2–4 record and 5.48 ERA with 42 strikeouts over 46 innings pitched. Wicks was optioned to Iowa to open the 2025 season. He was recalled by the Cubs for the first time during the season on April 18, and was optioned and recalled by the club various times throughout the year. Wicks made eight relief appearances for Chicago during the season, going 0-1 with a 6.28 ERA and 13 strikeouts over innings. With Iowa, he made 16 starts and went 3-4 with a 3.55 ERA. Wicks opened the 2026 season on the injured list with nerve irritation. ==Personal life==