From 1960 to 1970, Duffey was an assistant professor and then acting dean and associate professor at Hartford Seminary. He was also founder and director of the Center for Urban Studies there.
1970 election Duffey ran for the
U.S. Senate in 1970 as a prominent anti-Vietnam War candidate; he had just turned 35 years old. The campaign became notable because several of Duffey's young supporters went on to prominent careers in Democratic politics, including future president
Bill Clinton, a
Yale Law School student at the time. The
incumbent in that race,
Thomas J. Dodd, was the father of future Connecticut Senator
Christopher Dodd. Dodd, who had been censured by the Senate for corruption, was not re-nominated by the Democratic Party. Instead, Duffey joined Stamford businessman Alphonsus J. (Al) Donahue, State Senate President Edward Marcus, and former congressman
Donald J. Irwin in a race to win the party endorsement. Donahue won the Democratic convention, but Duffey went on to win the primary. He finished second in a three-way general election race to
Lowell Weicker, with Senator Dodd running as an independent. Some of these events were captured in a documentary,
Dissent of the Governed. Anne Wexler ran Duffey's 1970 campaign. They subsequently married in September 1974, after they had both divorced their respective spouses.
Academics Duffey was a fellow at
Harvard University's
John F. Kennedy School of Government in 1971. He went on to serve as an adjunct professor at
Yale University and a fellow at
Calhoun College from 1971 to 1973. During this time, he worked for the
George McGovern 1972 presidential campaign. He worked on the Carter–Mondale transition team between 1976 and 1977, and was Assistant Secretary of State for Educational and Cultural Affairs in 1977 and 1978. He served as chairman of NEH until 1982, when he became chancellor of the
University of Massachusetts Amherst. During his tenure the university welcomed
Robert Mugabe, granting him an honorary law degree ceremony in 1986 during which Duffey described Mugable as "an outspoken and effective leader in his country's sturggle for independence...laying the foundation for vibrant economy and interracial harmony". On June 12, 2008, the University of Massachusetts Board of Trustees revoked the honorary degree it had granted 22 years before based on Mugabe's history of human rights violations. Subsequently, the position of president of the entire
University of Massachusetts system was added to Duffey's responsibilities in 1990. One year later, he acted as joint head of the American delegation of
election observers in
Ethiopia. He was named as president of
American University in 1991 and served for two years. He subsequently joined
Laureate Education as senior vice president in 1999. There, he was responsible for education and academic quality and coordinated the development of
Laureate International Universities network programs and partnerships worldwide. ==Honors==