Successful
boy band DuJour, signed to the pop music
record label MegaRecords, are set to perform on a world tour. While on an airplane, they confront MegaRecords label executive Wyatt Frame to express concern about a strange backing track they have discovered on their single "DuJour Around the World". The band members subsequently get into a fight, and Wyatt parachutes out of the jet, leaving it to descend and presumably kill the band. Landing outside the town of
Riverdale, Wyatt searches for a replacement band. He plays DuJour's most recent track at a music store, causing the young crowd to respond to the
subliminal messaging, and causes the kidnapping of a "free-thinking" individual who dislikes the music. Wyatt eventually encounters the Pussycats: lead vocalist and guitarist Josie McCoy, drummer Melody Valentine, and bassist and backup vocalist Valerie Brown. The struggling local
pop-punk band and their manager, Alexander Cabot, accept Wyatt's offer of a major record deal despite its seeming implausibility, and they fly to
New York City. Wyatt renames the band "Josie and the Pussycats", arguing that the public needs to identify with the lead singer. Meanwhile, MegaRecords CEO Fiona, in an underground meeting with world government representatives, details how the
United States government has conspired with the music industry to hide subliminal messages in pop music to indoctrinate teenagers into buying trendy consumer products, thus helping to build a robust economy from the money the teenagers earn from minimum wage jobs such as babysitting. Musicians who discover the hidden messages are made to disappear via staged plane crashes, drug overdoses, controversial scandals, and similar disasters. Josie and the Pussycats' first single "Pretend to Be Nice" is released and, due to subliminal messaging, instantly becomes successful, soon topping the charts. However, Valerie increasingly resents the attention the label gives Josie rather than the band as a whole, while Melody's behavioral perception makes her suspicious of Fiona and Wyatt. Fiona orders Wyatt to kill Valerie and Melody before they uncover the conspiracy. The Pussycats are supposedly sent to an appearance on
MTV's TRL where
Carson Daly and his impersonator attempt to kill them with baseball bats, though the girls survive due to their attackers' incompetence. Rather than allow her to attend a gig by her friend Alan M., claiming it was cancelled, Wyatt instead gives Josie a copy of the group's latest single "You Don't See Me", which contains a subliminal message track designed to brainwash her into desiring a solo career. After arguing with her bandmates to the point where they leave, Josie realizes that the single caused the fight. Josie searches for Valerie and Melody, and with the help of Alexander and his sister, Alexandra, she confirms her suspicions when she uses a
mixing board to isolate the subliminal track. However, Fiona and her cronies catch Josie unaware. MegaRecords has organized a giant
pay-per-view concert that will be
streamed online, wherein they plan to unleash a major subliminal message via themed cat-ears headsets that viewers must buy to hear the audio. Fiona and Wyatt plan for Josie to perform solo while holding Melody and Valerie hostage, threatening to kill them in a staged car explosion if Josie does not comply. However, the badly injured members of DuJour arrive and thwart the pair's plan. It is revealed that DuJour survived the plane crash by landing the plane in the middle of a
Metallica concert, where they were severely assaulted by concertgoers, though Les of the group received fewer injuries due to his familiarity with "
Enter Sandman". Les also reveals that they sent Melody a message earlier warning her to "Beware of the Music". DuJour charges at Fiona, Wyatt, and their security guards only to stumble due to their injuries, giving Josie time to free Melody and Valerie. During the tussle, Fiona accidentally destroys the Megasound 8000, the machine used to generate the subliminal messages, revealing the new message to be one that would make Fiona universally popular. Fiona suffers a breakdown, revealing that her
lisp made her a social outcast in high school. Wyatt recognizes Fiona as Lisa "Lithping Litha" Snyder, a former high school classmate, and reveals that his own appearance and British accent are a disguise. He is actually an
albino, and his high school nickname was "White Ass Wally". The government agents colluding with Fiona arrive. However, with the conspiracy exposed, they arrest the pair as scapegoats to cover up their involvement in the scheme. They reveal that they were going to turn on Fiona regardless, as the government intended to abandon the idea of spreading subliminal messages via music, having decided that movies were a far more effective format. Josie, Valerie, and Melody perform the concert together. Alan M. arrives and confesses his love for Josie, who returns his feelings and kisses him onstage. The concert audience removes their headsets at Josie's suggestion and, able to judge the band on its own merits for the first time, roar their approval. ==Cast==