Eyisi said she was one of the weakest pupils in the class, with poor results in her early formal education. In other words, for her primary school education, she was enrolled at Central School,
Nnewi, but completed her First School Leaving Certificate at St Jude's Central School, Adazi-Ani, in 1981. In the same year, with a better Common Entrance Examination result, she was admitted to Girls’ High School,
Agulu, which was then under the leadership of Rev (Sr) Miriam Theresa Ozomma. She finished in 1986. Eyisi, as she is best cited in academia, bagged her National Certificate in Education (NCE) from
Anambra State College of Education,
Awka (1986–1989). She went for further studies at the
University of Nigeria, (UNN),
Nsukka,
Enugu, graduating with a
bachelor's degree (Second-Class Upper Division) in Education and English. After her national service in 1994, she was admitted for a master's degree programme in
Education Administration and School Supervision,
Nnamdi Azikiwe University, from where she graduated as the overall best student amidst a nation-wide
ASUU strike of 1995. Between 1997 and 2000, she went for MA/PhD at her Alma mater, UNN. Eyisi started her professional career as a part-time lecturer at Nwafor Orizuo
College of Education,
Nsugbe, though she had been a part-time lecturer at
Nnamdi Azikiwe University early in 1996. In 2000, the latter granted her appointment as a full-time lecturer. Her progress from Lecturer I to professorial rank on 1 October 2007 roughly took seven years to accomplish; hence she was adjudged the youngest professor in the university at that time. Eyisi's influence brought about the construction of the Department of English Language and Literature (situated close to
Nnamdi Azikiwe University's Faculty of Law) by a Nigerian transporter, Chief Godwin Ubaka Okeke (MON). She has been a Visiting/Adjust Professor in various tertiary institutions of learning, some of which are St Paul University, Awka, (2002–2005), and
Ebonyi State University,
Abakaliki the capital city of
Ebonyi State, southeastern Nigeria (2001–2005). ==Notable publications==