Depetris began his senior career with
Nueva Chicago, who signed him from
Argentinos Juniors in 2016. Depetris was promoted into their senior squad in July 2017, the final month of
2016–17, to be an unused substitute for fixtures with Argentinos Juniors, his ex-club, and
Instituto, prior to being selected for his professional bow on 28 July 2017 versus
San Martín; being subbed on for
Norberto Palmieri. Depetris departed at the end of 2018, subsequently having stints with regional sides Defensores de Salto and Centro de Formación Roma de Tigre. ==Career statistics==