Mena was born in
Vitoria-Gasteiz, in the
Basque Country. His brother Carlos is a
countertenor and his sister Elena is a research chemist. Mena began his music studies at the Vitoria-Gasteiz Conservatory. He later attended the
Madrid Royal Conservatory, where his teachers included
Carmelo Bernaola (composition and orchestration) and
Enrique García Asensio (conducting). He also studied conducting with
Sergiu Celibidache in Munich on a Guridi-Bernaola scholarship. In 1997, the
Basque Government selected Mena to form the Youth Orchestra of
Euskal Herria. He subsequently became associate conductor of the
Euskadi Symphony Orchestra. From 1999 to 2008, Mena was artistic director and principal conductor of the
Bilbao Symphony Orchestra. His guest-conducting debut in North America was with the
Baltimore Symphony Orchestra in 2004. Mena served as principal guest conductor of the
Teatro Carlo Felice, Genoa from 2007 to 2010. He was principal guest conductor of the
Bergen Philharmonic Orchestra from 2007 to 2013. In July 2010, the
BBC Philharmonic announced the appointment of Mena as its ninth chief conductor, effective with the 2011–2012 season, with an initial contract of three years, leading twelve concerts per year. Mena directed the BBC Philharmonic in four concerts prior to his appointment. In 2013, Mena extended his contract with the BBC Philharmonic for an additional 3 years. He concluded his tenure as chief conductor of the BBC Philharmonic in the summer of 2018. In 2016, the
Orquesta Nacional de España named Mena its new 'Director Asociado' (principal guest conductor). In October 2016, the
Cincinnati May Festival announced the appointment of Mena as its new principal conductor, effective with the 2017–2018 season, with an initial contract of 3 years. Mena stood down as principal conductor of the Cincinnati May Festival in 2023. In January 2025, Mena announced via social media his diagnosis of early-stage
Alzheimer's disease. His recent conducting appearances have included a June 2025 concert at the Granada Festival to mark the 100th anniversary of the revised version of
El amor brujo. Mena and his wife Noemi have two children. ==Awards==