In 2005, Doyle graduated from
Eugene Lang College. Alyssa Rosenberg, writing for
ThinkProgress in 2011, criticized Doyle's critique in Tiger Beatdown that year of the sexual violence in
Game of Thrones. Doyle is a feminist author; his first book, titled
Trainwreck: The Women We Love to Hate, Mock, and Fear... and Why (2016), particularly by classifying them as "crazy" and "
trainwrecks". In 2020, he published the teenage
horror comedy book
Apocalypse 1999 Or The Devil in Jenny Long, offering it as a free download via the book's website. In 2025 Doyle’s book about not leaving feminism after coming out as transgender, titled
DILF: Did I Leave Feminism?, was published. Doyle contributed "The Pathology of
Donald Trump" to the 2017 anthology ''Nasty Women: Feminism, Resistance, and Revolution in Trump's America
, edited by Samhita Mukhopadhyay and Kate Harding, and the piece “Nowhere Left to Go: Misogyny and Belief on the Left“ to the 2020 anthology Believe Me: How Trusting Women Can Change the World
, edited by Jessica Valenti and Jaclyn Friedman, as well as contributing to Rookie – Yearbook One
(2012), Rookie – Yearbook Two
(2014), and The Book of
Jezebel: An Illustrated Encyclopedia of Lady Things
(2013). Doyle also edited and wrote the introduction for Marilyn Monroe: The Last Interview: and Other Conversations
(2020). His piece "The Healed Body", about In My Skin, is part of the anthology It Came from the Closet: Queer Reflections on Horror'', published on October 4, 2022. Doyle was a staff writer for
In These Times and
Rookie, and has also written for other outlets including
The Guardian,
Elle,
The Atlantic, and
NBCNews.com. Doyle has written extensively about
sexual assault and the misogynistic abuse that many women face online, which Doyle has also endured. He wrote the comic
MAW, which was a five-issue horror series, the last issue of which came out in January 2022. The comic was released by
BOOM! Studios. Doyle wrote the horror comic series
The Neighbors, released by
BOOM! Studios in 2023. He was one of the writers for the comic
Hello Darkness #1, released by BOOM! Studios in July 2024. His story for that comic was called "Contagious". In June 2025 the horror comic series he wrote called
Be Not Afraid premiered; it was released by BOOM! Studios. He also wrote the five-issue comic book series
Dead Teenagers, the first issue of which came out in March 2026. He also worked on the
libretto for the musical
Queen of Hearts about
Martin Bashir’s interview with Diana, Princess of Wales; the musical premiered October 20, 2022. == Social media activities ==