Lowry made her stage debut in 1913 in a stock company in Washington, D.C. In 1921, she gave birth to her first child and retired from acting to raise her family. She resumed her acting career in 1952 after the youngest of nine children turned 18, appearing on stage and taking occasional bit parts in film and television. It was not until her eighties that she began to receive more substantial roles. Lowry played an uncredited part in
Valley of the Dolls (1967) as Aunt Amy, followed by roles in such films as
The Anderson Tapes and
Cold Turkey. Her best-remembered role is that of acid-tongued, no-nonsense Mother Dexter on the 1970s sitcom
Phyllis, starring
Cloris Leachman. This was Lowry's last major acting role. She died of a
heart attack during the series' final season. One of the last episodes she filmed before her death, "Mother Dexter's Wedding", marked the final appearance of veteran actor
Burt Mustin, who played her bridegroom, Arthur Lanson. By the time the episode aired in December 1976, Lowry had died at age 86, and the 92-year-old Mustin, who died in January 1977, was too ill to see it. After the airing of "Mother Dexter's Wedding", five more episodes of
Phyllis followed in which Lowry appeared. ==Death==