Missouri wine refers to wine made from grapes grown in Missouri. German immigrants in the early-to-mid-19th century founded the wine industry in Missouri, resulting in its wine corridor being called the Missouri "Rhineland". Later, Italian immigrants also contributed to the state's wine production. In the mid-1880s, wine was produced by volume in Missouri more than in any other state and just before Prohibition, Missouri was the nation's second-largest wine-producing state. Missouri had the nation's first American Viticultural Area (AVA) established on June 20, 1980 named Augusta. There are now ~four~ five American Viticultural Areas associated with Missouri: Augusta AVA, Hermann AVA, Ozark Highlands AVA, Ozark Mountain AVA, and the Loess Hills District AVA which extends into northwestern Missouri. In 2017 there were 125 wineries operating in the state of Missouri, up from 92 in 2009.