While still at graduate school, Chan gained a role in the
Global Television Network's
Rookie Blue (2010) (airing in the United States on
ABC). Between 2011 and 2017, Chan played regular series character Dr. Maggie Lin for five seasons on CTV's
Saving Hope, which was carried in the U.S. by
NBC. She appeared in the role of Sophia in
Silent House, a 2011 American horror film directed by Chris Kentis and Laura Lau, and the following year the romantic comedy film
Missed Connections. Chan has appeared in two Canadian television programs, miniseries
Bloodletting & Miraculous Cures and series
Republic of Doyle. In 2015, Chan appeared in the movie, ''
Ava's Possessions. Chan has also made guest appearances in episodes of Gotham (2016) and Schitt's Creek'' (2017). She hosted
The Great Canadian Baking Show with
Dan Levy, which premiered on 1 November 2017, on
CBC. Chan returned as host for the second season in 2018, but neither she nor Levy returned for the show's third season. On 21 February 2019, it was announced that she had landed the role of Pepper Smith in
The CW's
Katy Keene, a spin-off series of
Riverdale which started airing in 2020. She appears alongside
Lucy Hale,
Ashleigh Murray, and Jonny Beauchamp. In 2021, Chan appeared in the stage play
2:22 A Ghost Story. She appeared in
Archive 81 which premiered on
Netflix on 14 January 2022. In 2024, she was cast in the medical drama television series
Brilliant Minds. ==Personal life==