Durand ran for election to the legislature in the general elections of 16 November 1919 on the Democratic Union list, but was not successful. While still a municipal councilor for Besançon, and from 1922 a general councilor for the
Doubs department, he was elected to the legislature in the general elections on 11 May 1924. He ran on the Left Cartel list, and joined the Radical and Radical Socialist group in the chamber of deputies. He joined the committees on Civil & Criminal Legislation, and Commerce & Industry. From 1926 he chaired the committee on commerce & industry. He was a
Freemason, as were many French politicians in inter-war period. Durand was reelected in the second round in the general elections of 22–29 April 1928. He joined the committees on Customs and Commerce & Industry. In December 1929 Durand submitted a proposal for a decorative arts exposition similar to the 1925
International Exposition of Modern Industrial and Decorative Arts. He said that this exposition had helped France's balance of trade, spread French taste and fostered collaboration between artists and manufacturers. However, after the
Wall Street crash of 1929 there was less interest in a purely aesthetic exhibition, and more in one that focused on international cooperation. Durand was
Minister of Posts, Telegraphs, and Telephones from 21 February 1930 to 2 March 1930 in the short-lived cabinet of
Camille Chautemps. In the autumn of 1930 he chaired a committee that studied the organization of a European postal union. In 1931 he was appointed to the board of the Office of Foreign Trade, while chairing the committee on commerce and industry. He was reelected in the second round in the general elections on 1–8 May 1932, and was appointed
Minister of Commerce and Industry when the cabinet of
Édouard Herriot was formed on 3 June 1932. Durand participated in the
Lausanne conference on German reparations in June 1932. In October 1932 Durand's proposal for an exposition of the arts was combined with two others to form the basis for the 1937
Exposition Internationale des Arts et Techniques dans la Vie Moderne. Durand retained his ministry in the cabinet of
Joseph Paul-Boncour from 18 December 1932 until its fall on 28 January 1933. ==Later career==