Justicia gendarussa

J. gendarussa is an erect, branched shrub which belongs to the family of Acanthaceae. It is a dicotyledonous plant that can reach heights up to 1.5 m. Its leaves are lanceolate, 4–14 cm long and 1–2.5 cm wide. The color of the leaves can be white, green or grey and hairy on both sides. They are bitter, acrid and thermogenic. The capsule of J. gendarussa is about 1.2 cm long and smooth. The plant contains a wide range of biologically active compounds like flavonoids, alkaloids, steroids and phenolic compounds. == Cultivation ==

The plant prefers shadow and therefore is distributed in the forests of India, Malaysia and Sri Lanka. J. gendarussa is harvested from the wild. Because of its wide range of medicinal use, this causes jeopardizing of its natural biodiversity. Combined with the habitat destruction this uncontrolled harvesting causes the decline of the population. The silviculture presents a possibility for an improved production of J. gendarussa. Possible fertilizers are chicken manure and bamboo charcoal at a rate of 1.5 t/ha. The plant has a high root infection and strong mycorrhizal association. The arbuscular mycorrhizal fungus plays an important role for the soil fertility and the maintenance of the plant vigor due to its influence on microflora and nutrient cycle. The association with mycorrhiza can increase the growth and yield of the plant. == Medicine ==

J. gendarussa was proved to contain several phytochemicals, which are natural secondary plant compounds. Overall in the plant, roots, stem and leaves, following phytochemicals were found: alkaloids, flavonoids, tannins and phenols. The ingredients of the plant may vary depending on the age, physiological stage of the organ parts or the geographic region of cultivation. The plant was proved to have both anti-microbial and anti-fungal action on selected pathogen strains, and therefore this plant can be used to develop herbal drugs. The plant compound Patentiflorin A contained in J. gendarussa has shown to have a positive activity against several HIV strains, higher than the clinically used first anti-HIV drug, zidovudine AZT. Further, extracts of the leaves have an anti-inflammatory effect. This has been demonstrated especially in mice, specific for the carrageenan-induced paw edema. The juice of the leaves can be drizzled into the ear for earache. To treat external edema, an oil made from the leaves can be used. == Other uses ==

J. gendarussa can be considered as a potential phytoremediator. It can absorb high amounts of aluminium, iron and copper in leaves, roots and stems. The problem is that when the plant is used as a phytoremediator, it can no longer be used for medicinal use. == References ==