Establishment and early realignments K-61 was designated as a state highway by the State Highway Commission of Kansas (SHC) by 1928. At that time it began at US-54 by
Cairo and travelled north through
Preston. North of Preston, it turned east and soon entered
Turon where it turned north. The highway continued northward and ended at US-50S (modern US-50) by
Sylvia. On August 20, 1941, it was approved to build a new alignment of K-61 from Turon northeast through Langdon, Arlington and Partridge to Hutchinson. Before this, K-61 proceeded north from Turon to US-50S by Sylvia. On July 26, 1946, the SHC approved bids for grading, surfacing, building of three bridges, and seeding the shoulders on the section between Turon and Langdon. In a resolution on August 28, 1946, it was approved to build a new alignment of K-61 from US-54 just east of Pratt northeast to Preston. Before this K-61 traveled directly south from Preston to US-54. At the end of April and early May 1948, the SHC asked for bids to pave the new alignment from US-54 to southwest of Preston, and the section from Preston's east city limits northeast to Langdon's east city limits. On May 18, 1948, the SHC accepted a bid for the paving project. In the beginning of November 1948, the SHC asked for bids for grading, surfacing and bridges on a section of K-61 from slightly southwest of Arlington northeast for . On the 26th of that month, the SHC approved a bid for the project to proceed. The section from US-54 to Preston was finished by the end of 1948. On February 8, 1949, the city of Preston approved a $4,000 (equivalent to $ in dollars) bond to buy right-of-way for the section within the city. In May 1949, the SHC asked for bids for grading and surfacing from the north city limits of Preston southwest for . In early August 1949, the SHC asked for bids to build a section from Langdon northeast . On August 26, 1949, a bid was approved by the SHC for the segment to be built. In mid-April 1950, the unfinished section between Langdon and Arlington was opened to keep the dirt packed. Construction to finish the section was started in May 1950, with it being finished by summer that year. By September 28, 1950, this last section was almost completed. It had been supposed to open a few weeks earlier but was being delayed by rain, which was causing soft spots. The section opened to traffic the next day, which completed the new diagonal route between Pratt and Hutchinson.
Extension to McPherson K-61 originally ended in Hutchinson at US-50. On February 2, 1957, it was approved to truncate K-17 to Hutchinson and to extend K-61 along the former K-17 to US-81 in McPherson. From Hutchinson, it went northeast to Medora then turned east. K-61 continued east to Buhler, where it turned north. The highway continued north to Inman where it turned east. K-61 continued east to 14th Avenue then turned north and terminated at US-81 south of McPherson. This never happened and it remained the way the SHC planned. In mid-August 1957, the new diagonal section between Inman and Medora was opened to traffic. On February 12, 1958, it was approved to build a new alignment of K-61 from Inman directly northeast to McPherson. At the end of March, the SHC approved bids for grading of the section and for building three bridges on the project. On July 8, 1958, the SHC asked for bids for a base and surfacing of this new section. A few weeks later, the SHC approved a bid for paving the section of K-61. The new diagonal section between McPherson and Inman was opened to traffic on August 6, 1959.
Hutchinson rerouting In 1961, K-61 entered South Hutchinson from the west on Blanchard Avenue. It then turned north onto Main Street and crossed Arkansas River into Hutchinson. The highway continued north on Main to 30th Avenue where it curved east then northeast toward McPherson. At the end of May 1961, the SHC announced a project to for grading and a bridge on a new alignment of K-61 from what is now US-50 north to Avenue G in Hutchinson. Also a project for grading and bridges on a new alignment of K-61 and US-50 from K-17 to where K-61 currently turns north off US-50. Both projects were expected to begin after July 1 that year. On June 27, 1963, the SHC asked for bids for concrete pavement on the section of K-61 and US-50 and the section of K-61 from US-50 north to G Avenue. The next month a bid was approved for the concrete paving on both projects. By 1965, the section between US-50 and 4th Avenue had been opened. By 1967, K-61 was taken off of 30th Avenue and Main Street in Hutchinson. At this time the section between US-50 and Avenue G, and the section between 4th Avenue and 30th Avenue was four-lane. In mid May 1967, the SHC approved a bid for a project to add frontage roads at the junction with US-50 and to improve the intersections with 17th Street and 30th Street in Hutchinson. By 1971, the new four-lane section of K-61 and US-50 from K-96 west had been opened to traffic. By 1975, the entire section of K-61 from US-50 north in Hutchinson was four lanes.
Extension to I-35W K-61 originally ended at US-81 southwest of McPherson. In January 1965, construction plans were agreed on so that right-of-way acquisitions could proceed on the extension of K-61 to the new I-35W. In a resolution on August 24, 1966, it was approved to build I-35W (modern I-135) to the east of McPherson and realign US-81 onto it, to extend K-61 to the new I-35W, and to eliminate US-81 Alternate. Also in the resolution, the former section of US-81 from the new K-61 alignment north to US-56 remained in the state highway system. The section of former K-61 from the new K-61 to US-81, and former section of US-81 from there north to US-56 became K-61 Spur. The remaining section of US-81 was designated as K-61 Connector. The city of McPherson complained about the removal of US-81 Alternate. Then in a resolution passed on March 29, 1967, it was approved to re-establish US-81 Alternate in McPherson. On December 19, 1967, the SHC asked for bids to build the extension of K-61 that will link to the new I-35W. Bids were approved for grading, building nine bridges, and seeding the shoulders. On May 23, 1968, the SHC asked for bids to build a bridge to complete the interchange between I-35W and K-61. By the next month, work was progressing rapidly on the project. At the end of July 1968, the SHC approved a bid to pave the new stretch of roadway. By July 1969, the new I-35W had been built from the Saline-McPherson county line north to K-61. Also the section of the K-61 extension was opened from Main Street (modern US-81 Bus.) to I-35W. On November 20, 1969, the SHC asked for bids for improvements on a section from US-54 north for . At the end of that month, the SHC asked for bids to add lighting at the interchange with US-81 Business and the interchange with I-35W. On September 13, 1976, I-35W was renumbered to I-135. In an AASHTO meeting on October 13, 1979, it was approved to redesignate US-81 Alternate as US-81 Business within McPherson. The redesignation was approved by KDOT on April 1, 1981.
Improvements As early as September 1964, the section of K-61 between Hutchinson and McPherson was planned to become a four-lane freeway. In a resolution passed on September 9, 2009, it was approved to rebuild and realign K-61 in Reno and McPherson counties from Hutchinson northeast to the junction with K-153 Spur. The new alignment of K-61 would be built as a four-lane divided highway with some intersections changed to grade-separated interchanges, and the number of at-grade intersections reduced. The original route went through Medora and Inman, but the new route would bypass both, west of its original route. On May 5, 2012, the new section in Reno County opened to traffic, with southbound traffic switching over around 12 p.m. and northbound traffic switching over at 3 p.m.; the pedestrian bridge over the highway was completed later in 2012. The $105.3 million (equivalent to $ in dollars) project was completed by Koss Construction of Topeka. In 2013, the new section of the highway was designated the John Neal Memorial Highway in memory of a major advocate of the project. ==Major intersections==