In 1956, Ramesh joined the Archaeological Survey of India as an epigraphical assistant and was posted to
Ootacamund. He became the Deputy Superintending Epigraphist of the
Chennai circle in 1966, Superintending Epigraphist in 1976 and Chief Epigraphist in 1984. As Superintending epigraphist, Ramesh succeeded
G. S. Gai as the editor of ASI's bulletin
Epigraphia Indica and edited the last two volumes in 1975-76 and 1977-78. Ramesh became the Joint Director General of the ASI in May 1992 and served until his retirement in June 1993. Post-retirement, Ramesh served as the Honorary Director of the
Oriental Research Institute, Mysore from 1998 to 2006. He was the first one to have deciphered a 12th century
Sanskrit inscription at the
Ram Mandir site in
Ayodhya, which proved the existence of a temple at the site before the
Babri Masjid was built over it. == Views on Tamil-Brahmi ==