Santos Born in
Olinda,
Pernambuco, Kaio joined
Santos' under-11s in 2013. On 21 September 2018, Kaio was promoted to the first-team by manager
Cuca. He made his professional – and
Série A – debut nine days later, coming on as a second-half
substitute for
Bruno Henrique in a 1–0 home defeat of
Atlético Paranaense, becoming the sixth youngest to debut in Santos' history. On 11 January 2019, after lengthy negotiations, Kaio signed his first professional contract with the club, agreeing to a three-year deal. He scored his first goal for
Peixe on 3 March of the following year, netting his team's second in a 2–1
Copa Libertadores away win against
Defensa y Justicia; it was also his debut match in the competition.
Juventus On 26 July 2021, Kaio reportedly agreed to a pre-contract with Italian side
Juventus, effective as of 1 January. On 2 August, Santos announced an agreement with Juventus for his immediate transfer, with the Italian side paying a rumoured fee of
€3 million. Juventus officially announced Kaio's transfer on 17 August, signing him on a five-year contract. On 23 August, Kaio suffered a medium-grade injury to the
rectus femoris. On 1 September, Kaio was excluded from Juventus' 23-man squad for the
UEFA Champions League group stage. He played his first match since this injury (and the first one for Juventus) on 2 October, in a 1–0 away win against
cross-city rivals Torino, coming on as substitute in the 89th minute. On 20 October, Kaio played a match with
Juventus U23 — the reserve team of Juventus — in a 2–2
Serie C away draw against
AlbinoLeffe, where he missed a
penalty and scored a goal. In January 2022, Kaio refused a loan move to
Sassuolo. On 2 February, Juventus' coach
Massimiliano Allegri did not include Kaio in the
UEFA Champions League knock-out stage squad. Kaio was called up by Juventus U23 again on 22 February, for a match against
Pro Patria set to be played the following day, where he injured his
patellar tendon. He ended the
2021–22 season early, having only played 125 minutes in nine matches with the first team (none as a starter).
Loan to Frosinone On 29 August 2023, Kaio joined newly promoted side
Frosinone on a season-long loan.
Cruzeiro On 6 June 2024,
Campeonato Brasileiro Série A club
Cruzeiro announced a verbal agreement with Juventus and Kaio Jorge's staff for the transfer of the player. The deal was officially confirmed five days later after the completion of the medical exams, with Kaio Jorge signing a five-year contract with the club. ==International career==