Early years (2010–2014) monument in Clifton is featured on the club crest|left|209x209px The club was formed in 1996 by Taha Alizai in Karachi. The women's team was established in 2010, with the goal of creating a national team capable of representing Pakistan at the
FIFA Women's World Cup. In September 2016, the women's team represented Pakistan at the International Women's Football Cultural Festival in
Berlin.
Top-flight (2014–present) Karachi United Women finished as runners-up at the
2019–20 National Women Football Championship against Army, and were in the semi-finals of the
2021 National Women Football Championship before the tournament was cancelled. Saima Baig, former Pakistan Army player, was appointed as the head coach for the team in 2023. Karachi United Women finished in third place at the
2024 National Women Football Championship. They topped their group in the Karachi leg by winning both matches as well as the Islamabad leg by winning 3 matches. A semi-final defeat to Legacy WFC resulted in the team playing the
third place playoff against Hazara Quetta WFC, which they ultimately won.{{Cite web |title=Hazara, Legacy march into semis of National Women's Football Club Championship 2024 == Crest and colors ==