Boccalero founded and named Self-Help Graphics in
Boyle Heights in 1971, with a group of Chicano artists. She had acquired a printing press and started a workshop in a garage rented by her order, the
Sisters of St. Francis of Penance and Christian Charity. Self-Help Graphics was both a print studio and a community center, with Sister Karen as its longtime director. She worked to highlight Mexican cultural elements in much of the studio's output, and in the educational programs that they undertook. She was instrumental in organizing the first Dia de los Muertos celebration in Los Angeles. "Sister Karen was very adamant about including Mesoamerican and Mexican iconography and history in teaching young people in East L. A.," noted instructor
Linda Vallejo. Boccalero was a persuasive fundraiser for the program. Her training as an artist informed her work supporting emerging artists. She considered the studio her mission, as a Franciscan nun, and her order recognized it as such, even while she was supporting
Willie Herrón in bringing East Los Angeles
punkero bands to perform regularly in the studio. In 1988, Boccalero won a Vesta Award from the
Woman's Building, for her work in arts community support. Boccalero lived to see Self-Help Graphics featured in a major exhibit at
Laguna Art Museum in 1995. ==Personal life and legacy ==