The school was established on 22 April 1971 following a formal notification from
Mom Chao Chakrabandhu Pensiri, then-Rector of Kasetsart University, to the Ministry of Education. Its foundation aimed to provide a comprehensive educational institution that allows children to develop to their full potential while also serving as a field base for teacher training for university students and as a hub for educational research. Developed based on the progressive laboratory school concept pioneered by
John Dewey, the school's founding principal was Ubol Reangsuwan, a prominent figure in Thai education. She led an initial faculty comprising experienced educators transferred from
Chulalongkorn University and the Ministry of Education, as well as 37 newly recruited teachers. Since its inception, the school has been associated with the development of inclusive and innovative learning approaches in Thailand. Currently, Kasetsart University Laboratory School holds the status of the Center for Educational Research and Development, functioning as an entity equivalent to a department within the Faculty of Education at Kasetsart University. == Directors ==