As a junior, she won the
1998 Wimbledon singles title and was runner-up at the
US Open. Srebotnik was ranked No. 2 in the junior rankings in 1997 and 1998. She was mentored by
Gabriela Sabatini.
1995–1999: WTA Tour debut and historic Guinness world record Srebotnik made her debut on the
ITF Women's Circuit in 1995, winning the singles tournaments in Ismailia in 1996, Zadar in 1997 and Šibenik in 1998. In 1998, Srebotnik won the doubles title on her
WTA Tour debut at the
Makarska Open (with
Tina Križan), and later that year reached the doubles final at the
Austrian Open, also with Križan. In 1999, her win at the ITF tournament in Dubai gave her direct entry into her first tour-level singles event in
Estoril, where she became the fourth player to win on her tour debut, defeating
Rita Kuti Kis in the final. She broke into the top 100 on April 12, 1999 at No. 88. In May 1999, Srebotnik played in her first Grand Slam singles main draw at
Roland Garros, losing to
Arantxa Sánchez Vicario in the second round. She won her first Grand Slam title in the mixed doubles with
Piet Norval, becoming the first woman ever to win her first tour event in singles, doubles and mixed doubles. Only
Mirjana Lučić had previously won on debut in both singles and doubles.
2000–2004 Srebotnik reached her first Tier-I semifinal in Tokyo at the
Pan Pacific Open, which she lost to
Sandrine Testud. On 7 February 2000, Srebotnik broke into the top 50 at No. 49. She won her fourth career doubles title at
Estoril (with Tina Križan). Srebotnik and Križan won their only doubles title of 2001 at Hawaii. They reached their biggest doubles final of their career in Toronto at the
Canadian Open by defeating
Martina Navratilova and Arantxa Sánchez Vicario in the semifinals, and they were doubles finalists at Estoril. They qualified for their debut doubles season-ending championships. Srebotnik reached a doubles ranking of No. 19 on 8 October. In 2002, Srebotnik reached the finals at
Bogotá (losing to
Fabiola Zuluaga) and
Acapulco (defeating
Paola Suárez) in the final. She reached the fourth round at
Roland Garros, which is her career-best Grand Slam performance. Srebotnik later achieved her then-best win at Los Angeles by defeating world No. 6,
Kim Clijsters. She reached the semifinals in
Luxembourg. She achieved her second appearance at the doubles season-ending championships with Križan. 2003 saw Srebotnik reaching her fourth tour final at Palermo. She won the Bogotá doubles title with
Asa Svensson, and reached her second Tier I quarterfinals in Toronto at the Canadian Open. She won her second Grand Slam mixed-doubles title at the
US Open, this time with
Bob Bryan. Her 2004 season was highlighted by reaching the semifinals at Palermo, and the quarterfinals at
Strasbourg and
Forest Hills. Srebotnik won her seventh doubles title in Tokyo at the
Japan Open (with
Shinobu Asagoe).
2005 Her best season to date was highlighted by two singles and four doubles titles as well as a career-best victory over
Amélie Mauresmo. Srebotnik captured her third and fourth career WTA Tour singles titles at
Auckland (defeating Shinobu Asagoe in the final, and she teamed with Asagoe for the doubles title) and in
Stockholm (defeating world No. 14
Anastasia Myskina in the final and teaming with
Émilie Loit for the doubles title). She was the only player in 2005 to sweep singles and doubles titles twice. She also finished runner-up at
Portorož, losing to
Klára Zakopalová (now Koukalová) in three sets in the final. She also became runner-up in doubles with
Jelena Kostanić. Srebotnik reached the quarterfinals five times: at Tier II at
Antwerp (lost to
Anastasia Myskina), Tier I
Charleston (losing to
Elena Dementieva in three sets),
Budapest (losing to
Laura Pous Tió in a third set tie-break), Tier I
Zurich (losing to Ana Ivanovic), and Hasselt (losing to
Dinara Safina in a third set tie-break). Her best finish in a major was a third-round loss at
Wimbledon to
Maria Sharapova. A new career-high singles ranking of No. 28 came on 7 November. In addition to Auckland and Stockholm, Srebotnik won doubles titles at Budapest and Hasselt (both with Émilie Loit). She reached the
US Open mixed-doubles final (with
Nenad Zimonjić, losing to
Daniela Hantuchová and
Mahesh Bhupathi).
2006 Srebotnik opened the 2006 season with an early exit at the
Auckland Open. Two weeks later at the
Australian Open, with partner Shinobu Asagoe, she made it to the semifinals in doubles, losing to
Yan Zi and
Zheng Jie. She won doubles titles in
Antwerp (with Dinara Safina) and
Amelia Island (with Shinobu Asagoe). At the French Open, she won the
mixed doubles championship with Nenad Zimonjić. At the
US Open, she reached the doubles final partnering Dinara Safina. In
Stuttgart, she reached the semifinals in doubles with Dinara Safina. At the
Zurich Open, Srebotnik reached the semifinals of a
Tier I tournament for the first time in six years (Pan Pacific Open, Japan). Also, Srebotnik and
Liezel Huber reached the doubles final. In her final event of the season at the
Linz Open, Srebotnik reached the doubles final with
Corina Morariu.
2008 At the
French Open, Srebotnik caused an upset when she defeated Serena Williams, whom she had never beaten in four previous attempts, in the third round. At the
US Open in the same year, she upset former champion Svetlana Kuznetsova in the third round. On both occasions, she lost to
Patty Schnyder in the next round.
2010 In that year, Srebotnik teamed with
Květa Peschke, and won the WTA tournaments of
Indian Wells (defeating Nadia Petrova and Sam Stosur in the final) and
New Haven (defeating
Bethanie Mattek-Sands and
Meghann Shaughnessy), and reached the final of the
WTA Championships in Doha. Srebotnik had an excellent doubles outing at the
French Open. In the ladies' doubles, she and Peschke defeated the second seeds
Nuria Llagostera Vives and
María José Martínez Sánchez in the semifinals, but lost to Serena and Venus Williams in the
final. She also partnered with Nenad Zimonjić to win the
mixed doubles title with a thrilling tiebreak win against
Yaroslava Shvedova and
Julian Knowle. Srebotnik and Peschke reached the final at the
Rogers Cup. It was the second time this year that Srebotnik and Peschke reached a final of a Premier-5 tournament after
Dubai in February. At the end of the 2010 season, Srebotnik announced that she would focus on doubles for the remainder of her career.
2022: Retirement Although she played her last match at
Roland Garos in 2020, she was officially honored for her career in Portorož in September 2022. ==Grand Slam finals==