In September 2017 McGuire was nominated as Assistant Secretary for Congressional and Intergovernmental Affairs at the Labor Department. Her nomination passed the
Senate by
voice on December 21, 2017. She resigned from her position on January 15, 2019. Prior to her confirmation, she was the
chief of staff to U.S. Representative
Randy Hultgren. McGuire previously served as staff director of the
United States Senate Committee on Health, Education, Labor and Pensions under
Mike Enzi. She also served as Enzi's legislative director and as staff director of the
United States Senate Committee on Banking, Housing, and Urban Affairs. She has held posts with
Alan K. Simpson and
Richard Lugar. McGuire's private sector experience includes leading
BSA (The Software Alliance)'s global public policy and government relations division as vice president. In January 2019, the
American Psychological Association announced McGuire's appointment as its first Chief Advocacy Officer. == Education ==