Ferrara was appointed to the faculty at the
University of Virginia in 1989. In 1998 Ferrara returned to the
University of California, Davis. In 2000 Ferrara founded the University of California, Davis Department of Biomedical Engineering, supported by a $12 million award from the
Whitaker Foundation. When she stepped down as Head of Department in 2005, the new department had risen to the 23rd in the United States. At University of California, Davis, her research considered cancer diagnosis and image-guided drug delivery. Image-guided drug delivery makes use of medical imaging methods (including
positron emission tomography and
magnetic resonance imaging) to target drug delivery.
molecular imaging, ultrasound
thermometry and image guided therapies. In particular, Ferrara has focussed on
ultrasound therapy guided with magnetic resonance imaging, nanoparticle based cardiovascular imaging and image-guided drug delivery. A challenge in cancer therapeutics is that the treatments are often toxic, and getting high enough doses to diseased tissue can result in significant damage. To focus ultrasound for
chemotherapy and immunotherapy Ferrara combines an annular array and
Bruker MRI. Ferrara makes use of nanoparticle encapsulation and ultrasound to achieve high target-to-background imaging. Alongside their work on cancer, the nanoparticles developed by Ferrara and co-workers can be used to image and deliver
microRNA treatments for the treatment of damaged heart tissues. In 2018 Ferrar joined
Stanford University as a professor of radiology. At Stanford Ferrara has explored the use of microbubbles injected with a therapeutic agent as a treatment for
breast cancer, using ultrasound to selectively destroy the microbubbles (through resonance) when they reach the appropriate location. == Awards and honors ==