O'Regan made her
West End debut in a production of
Persevering Pat. She was in the first London productions of the
Sean O'Casey plays
Juno and the Paycock and
The Plough and the Stars. in
A Night in June,
Young Woodley, and
Tinker Tailor in 1928, and in comedies including the
farce Two Deep in 1930. A 1928 reviewer noted that O'Regan "has already a personality that can express and convey emotion, fine eyes, repose, and beautiful movement," while suggesting that she "learn our silly way of speaking English if she is to play English parts." and the all-Irish film
Ireland Through the Ages (1930),
Fires of Fate (1932), and
Rose of Tralee (1938). On radio, she was heard in adaptations including
The Four Feathers. O'Regan was considered a stylish stage beauty. She endorsed Lux soap in print advertisements that highlighted her "satin-smooth" complexion. She continued on the stage through the 1930s and into the 1940s, appearing in
Eight Bells (1933),
And a Woman Passed By... (1935)
Ben Travers's farce
Banana Ridge (1938), and
The Crime of Margaret Foley (1947). ==Personal life==