Following her residency, Cho became an Instructor in the Department of Pathology at Johns Hopkins University before being appointed to the rank of
assistant professor in the Departments of Pathology, Oncology, and Gynecology and Obstetrics in 1991. She remained with Johns Hopkins until 1998 when she accepted an
associate professor position at the
University of Michigan. Following her promotion to Full professor with tenure in 2002, Cho's laboratory developed a mouse model to research ovarian endometrioid adenocarcinoma. From 2013 to 2014, Cho served as Interim Chair of the University of Michigan's Department of Pathology. Following this, she was elected a member of the
National Academy of Medicine for both her diagnostic expertise and laboratory research in gynecological cancer. In 2017, her research team used genetically modified mice to mimic tumors that closely resembled human high-grade serous carcinomas. ==Personal life==