Bainbridge enjoyed a series of prestigious fellowships after graduation. He was awarded a
National Research Council, and then a
Bartol Research Foundation fellowship. At the time the
Franklin Institute's Bartol Research Foundation was located on the
Swarthmore College campus in Pennsylvania, and was directed by
W. F. G. Swann, an English physicist with an interest in
nuclear physics. Bainbridge spent four years (1929-1933) at the Franklin Institute’s Bartol laboratories and during his time there Bainbridge learned how to take subtle and difficult mass measurements. He used this instrument to verify
Albert Einstein's
mass–energy equivalence, E = mc2. Since Bainbridge was the first to successfully test Einstein’s theory of the equivalence of mass and energy, he was awarded the Louis Edward Levy Medal. One of the cyclotron's most notable experiments was in
nuclear transmutation, specifically the
synthesis of precious metals including
gold, which Bainbridge and his collaborators
Rubby Sherr and
Herbert H. Anderson announced in 1941. Bainbridge was elected a Fellow of the
American Academy of Arts and Sciences in 1937. His interest in mass spectroscopy led naturally to an interest in the relative abundance of
isotopes. The discovery of
nuclear fission in
uranium-235 led to an interest in separating this isotope. He proposed using a
Holweck pump to produce the vacuum necessary for this work, and enlisted
George B. Kistiakowsky and
E. Bright Wilson to help. There was little interest in their work because research was being carried out elsewhere. Bainbridge ended up bringing his Holweck pump to government authorities in Washington D.C., however the government authorities claimed that scientists working for the government were already working on a process of isotope separation and that he should discontinue his work using the Holweck pump for
isotope separation. In 1943, their cyclotron was requisitioned by
Edwin McMillan for use by the U. S. Army. It was packed up and carted off to
Los Alamos, New Mexico. ==World War II==