KY 6 begins at an intersection with
KY 26 in
Woodbine,
Whitley County, heading southeast as a two-lane undivided road that immediately crosses a
CSX railroad line. After the railroad tracks, the route turns to the southwest for a short distance before heading to the southeast along Barbourville Road. KY 6 passes homes and some businesses before leaving Woodbine. The road heads into a mix of fields and woods with some homes, intersecting the southern terminus of
KY 3606 before reaching a junction with the northern terminus of
KY 1064. The route heads through more rural areas and curves to the east, crossing into
Knox County. ==Major intersections==