Khon Kaen Football Club was publicly formed on 21 June 2007, before that time the club played in the
Provincial League which largely consist of regional football clubs, nonetheless, the league was not recognized by the
Football Association of Thailand. In 2007 the league was merged into
Thai Premier League and
Thai Division 1 League and the club was registered to be professional football club in this year and was allocated into Thai Division 1 League Group A, the club was close to promotion by finishing at the fourth place that season. In the 2008 season, Khon Kaen was not performing as well as the previous season as they could only finish the season in 8th place, nevertheless, the club proved themselves, being one of the favourites for promotion in the 2009 season, however, they lost the promotion spot to
Sisaket in the last week of the season. In 2010, the club was finally promoted to the
Thai Premier League after finishing runners-up in the league table which was the first time for the club to participate in the top flight of Thai football. However, their brief
TPL tenure ended disappointingly as they finished bottom of the table. Any thoughts of yo-yoing straight back never emerged in
2012 with the T-Rex finishing in the bottom half of the first division. In 2014, the Club got 17th of
2014 and relegated to
2015 Thai Division 2 League North Eastern Region into North-Eastern zone. In 2022, Khon Kaen competed in the
Thai League 3 for the 2022–23 season. It is their 17th season in the professional league. The club started the season with a 3–0 away win over
Nakhon Ratchasima United and they ended the season with a 1–0 home win over
Nakhon Ratchasima United. The club has finished 4th place in the league of the Northeastern region. In addition, in the
2022–23 Thai FA Cup Khon Kaen was defeated 2–3 by
Phrae United in the third round, causing them to be eliminated and in the
2022–23 Thai League Cup Khon Kaen was defeated 0–1 by
Khon Kaen Mordindang in the second qualification round, causing them to be eliminated too. Later on July 31, 2025, Kasom Chanawong, the club presidents, announced that he would pass on the position of club presidents to the famous singer and actor, Tono
Phakin Khamwilaisak, while Kasom moved up to become the club's advisory chairman. ==Stadium and locations==