In June 2019, Boom! Studios announced SIKTC as a five-issue limited horror series (with artist Werther Dell'Edera) to debut that September. Tynion later said the concept, about monsters that prey on children and the one hunter who can see them, had "been living in my head for a long, long time". The announcement explained that the story was set in a small town (Archer's Peak, Wisconsin) beset by child deaths and disappearances, and a mysterious outsider, Erica Slaughter, who claims she can stop the killings.
Something Is Killing the Children #1 was released on September 4, 2019. Even before release, the book had gone to second and third printings. By October 2019, Boom went to a fourth printing of issue #1. The company's Sales & Marketing President Filip Sablik announced it was "the top-selling original series launch in our history". The publisher upgraded the title from a limited series to an ongoing monthly book before issue #1 was in shops. In June 2024, Tynion said that he and Dell'Edera plan to continue the series for many more issues, potentially even beyond a hundred. That same year Tynion said that he hopes the success of
SIKTC well help move the comics industry back towards more longform creator-owned series again, as he believes the longform serial is one of the greatest strengths of the American direct market. As part of the series' fifth anniversary, Boom announced
SIKTC #0, which explores the backstory of the mission Erica took before heading to Archer's Peak. Like the first issue,
SIKTC #0 sold out at the distributor level.
Spinoff titles Something Is Killing the Children (
SIKTC) spurred a franchise coined "the Slaughterverse". In May 2021, Boom Studios released the
one-shot Enter the House of Slaughter as part of
Free Comic Book Day, which functioned as an introduction to the upcoming series,
House of Slaughter. House of Slaughter launched in October 2021 and it explores the Order of St. George that forged Erica Slaughter into a monster hunter. The first arc, "The Butcher's Mark," was written by Tynion alongside Tate Brombal, with Dell'Edera co-plotting and Chris Shehan on art. It's told from the perspective of Erica's handler Aaron, who, as a teenager training at the House of Slaughter, meets Jace Boucher, the sole survivor of the House of Butcher. Tynion explained that, after
SIKTC #5, he "knew there was an entire world of monsters and monster hunters outside of Erica Slaughter's story," so he called in Brombal and Shehan to "tell this exciting new story introducing everyone to the hunters Erica grew up alongside".
House of Slaughter ran for thirty issues through February 2025. The series alternated between two ongoing storylines, which focused on Jace Bourcher and different mask types. On December 28, 2022, the oversized one-shot
Book of Slaughter #1 was published. This was the first in the
Books of Slaughter series, which focuses on Maxine Slaughter's journey in Europe. It was followed by
Book of Butcher #1 on December 27, 2023, and
Book of Cutter #1 on January 29, 2025. Though the
House of Slaughter and
Books of Slaughter series have finished, Tynion has said that he and Dell'Edera have plans for more spinoffs. At
New York Comic Con 2025, the spinoff
Fall of the House of Slaughter was announced for 2026. The title is a reference to
Edgar Allan Poe's
"The Fall of the House of Usher".
Art book In December 2024, Boom Studios published
The Art of Something Is Killing the Children. The book explored the creation of the seven arcs spanning issues #1–35 with creators Tynion and Dell'Edera interviewing each other throughout. It also contains a selection of covers and some of Tyion's scripts. Editor Eric Harburn indicated in the art book's introduction that he wishes to do further volumes, a point which he later clarified and reiterated on BlueSky.
Crossover In October 2025, a crossover with
DC Comics'
Black Label imprint was announced for 2026, entitled
Swamp Thing Is Killing the Children. Tynion will write the miniseries with Dell'Edera providing the art. ==Awards and nominations==