Killisnoo was an unincorporated community on Killisnoo Island in the Hoonah-Angoon Census Area in the U.S. state of Alaska, near Angoon, Admiralty Island. Killisnoo had a post office until it closed in 1930. The community was known by several alternative names, including Kanas-nu, Kanasnu, Kenasnow and Killishoo.