In his thesis (
Experimental chemical cancer) of 1942 he studied tar-induced cancer in rats. Later on, the range of research topics widened to include the pathology of the heart and the blood vessels, the tumors of the heart, the pathology of the digestive tract, of the liver and the pancreas, the pathology of the infant, pre-cancerous states and in situ cancer, the pathology of the mouth (in particular
Lichen planus), accidental and professional exposure to toxins (in the late 1960s and early 1970s doing an in-depth study of the toxic (carcinogenic) nature of the environment of
Copşa Mică), toxic reactions to
phenylhydrazine, hypertoxic forms of viral disease, suppurating pulmonary infections,
cerebrotendineous xanthomatosis, visceral lesions in
rheumatic disorder and
rheumatoid arthritis,
trichinosis, the reactions of the gastric mucosa to
aspirin, and to aspirin combined with
prednisone, experimental research in
syphilis and in
trichinosis,
sudden infant death syndrome, and on
hypertrophic cardiomyopathy caused by hypersecretion of
adrenocortical hormones. He pioneered the pathological study of the effects of
dental implants on the oral cavity, in collaboration with Dr. Grigore Osipov-Sinești (1907-1989) and with Ernst Helmut Pruin (1913-2008) and Benedict Heinrich. ==Recognition==