Due to geographically unstable terrain on the route, traffic on parts of the line was suspended six times after tunnels sustained damage. Unlike the conventional-speed
Lanzhou–Xinjiang railway the line is routed via Xining, the capital of Qinghai, a major city and the start of the
Qinghai–Tibet railway.
Wind shed risk Near
Shanshan, the railway passes through the
hundred-li wind zone, where desert wind constantly blows most days of a year. In 2007, strong wind overturned a train on the southern branch of the older conventional rail
Lanxin Railway, and four people were killed. A long wind-protection gallery has been built next to the tracks in this region.
Engineering issues Many sections of the line have experienced roadbed settlement, deformation, subsidence, frost heave, and cracking of the concrete of the track bed caused by
saline soil, large temperature differences, and extremely low temperatures. The -long Zhangjiazhuang Tunnel, located between Minhe South and Ledu South stations, was damaged several times during operation. The tunnel is embedded in
mudstone, interbedded with
sandstone and
gypsum rock. The top covering soil layer is
loess. In 2016, the tunnel was damaged twice, closing the line for 3 months. After reopening, the operation speed in the tunnel was limited to . On December 24, 2018, the mountain above the tunnel deformed, but trains could initially continue operating. However, the next day, after further deformation, the tunnel was closed for thorough inspection. Due to repair works, the line was closed between Lanzhou and Xining until October 11, 2020. Trains were routed over the lower speed
Lanzhou–Qinghai railway.
Earthquake damage As a result of the
January 2022 Menyuan earthquake, some bridges and tunnels on the line sustained serious damage. The section between and was halted until repairs could be completed.
Landslide In September 2022, traffic on the line was suspended just north of Xining after a landslide caused the deck of a viaduct to shift. ==Economics==