Vetterlein's early interest in football was inspired by her sister Alisa. She joined SV Nollingen's
youth system when she was five years old and got a special permit from the
German Football Association to keep playing in boys' youth teams until she was 16. She began her senior career in 2008, electing to join
1. FC Saarbrücken who had just been
relegated from the
Frauen-Bundesliga and were looking to give younger players a chance in their team. Vetterlein played 48 league matches for Saarbrücken over three seasons and helped them reclaim their place in the top division. But when they were relegated again in 2011 she
transferred to
Wolfsburg, where her sister was also contracted. Wolfsburg won the
UEFA Women's Champions League in consecutive seasons, but Vetterlein was an unused
substitute in both the
2013 and
2014 finals. When her contract was not renewed she agreed a
free transfer to
SC Sand in May 2015, alongside Wolfsburg teammate
Jovana Damnjanović. In July 2019 Vetterlein signed for
FA Women's Super League club
West Ham United. ==International career==