House of M Layla Miller is first seen as a young mutant girl who lives in
Hell's Kitchen in
New York City. When she wakes up one morning, she finds
everything has changed and she is one of a small number of unaffected characters. Layla is instrumental in bringing down the "House of M" by using her ability to restore the memories of superheroes who rebelled and helped restore reality.
Doctor Strange suggested that
Scarlet Witch, who created the House of M reality, created Layla as a
failsafe to help the heroes in case something went wrong.
X-Factor Investigations After Layla joins X-Factor Investigations, she takes steps to deal with Singularity Investigations, a rival investigations firm. When X-Factor have their final showdown with Singularity Investigations, she helps uncover the fact that
Guido Carosella had been brainwashed by them at some point in his past while rescuing a client.
Jamie Madrox organizes all X-Factor members to see
Doc Samson for psychiatric evaluations; they play chess and she reveals she is willing to make sacrifices for the greater good and that even she is expendable.
X-Cell and Nicole A group made up of ex-mutants by the name of X-Cell, who believe the government has depowered mutants, hides in
Mutant Town. When
Siryn and
Monet return from
France, they bring an ex-mutant named Nicole, which shocks Layla because she did not know of her arrival. Layla visits Quicksilver, who had restored most of X-Cell's powers. She reveals to
Callisto and
Marrow that it was he and Wanda Maximoff who caused the Decimation; the government did not depower them, and Pietro has lied. After a failed attempt on Layla's life, Nicole is tripped by Layla and falls in front of a train, which destroys her, revealing she was actually a robot. Around this time,
Daisy Johnson offers Layla to join
Nick Fury's
Secret Warriors, but she declines, claiming the mutants will need her more.
Messiah Complex Layla goes with one of Jamie's dupes to investigate an alternate future caused by the birth of the mutant messiah. While there, they discover that the mutants are living in
internment camps. While in an internment camp, the mutant scanners alternate between detecting Layla as a mutant and as a human. They learn from a child version of
Bishop that the mutant messiah had caused this world. Layla kills the dupe to send the information back to the original Jamie, leaving her alone and stranded in the future. Layla eventually returns to the past, though she is considerably older than when she had departed. Assuming the guise of a nun, she begins working alongside John Maddox, a duplicate of Jamie Madrox who had chosen to live a domestic life with his family. Upon arriving at John's church, Layla encounters Jamie at the moment he is attempting to take his own life. She intervenes, prevents the act, and discloses her true identity, leaving Jamie visibly shocked. After Layla and Jamie argue about how they never came for one another, the two finally give into their emotions and share a kiss. Jamie is awkward about starting a relationship with Layla, feeling she is still a child, though Layla tells him she never really was. Layla, Jamie, and
Ruby Summers go find an old, frail
Doctor Doom, requesting his help with time travel. Doom reveals he has met Layla before and informs the trio about
Doomlocks. They are then attacked by
Sentinels and saved by
Trevor Fitzroy. They bring the frail Doom back to their stronghold in Atlantic City where she gets into an argument with Cyclops about bringing him with them and Fitzroy's future. Taking Doom to an old lab, he creates a Doomlock and turns on them, bringing forth Cortex, a rogue clone of Jamie. Cortex kills Fitzroy, and Ruby asks Layla if she can bring him back. Layla reveals that she has the ability to resurrect the dead at the cost of their soul, conscience and morality. Following the conclusion of the battle, Layla explains the nature of her powers to Jamie. The two are displaced in time by a Doomlock device: Jamie is returned to X-Factor, while Layla is transported to a point in time prior to her involvement with X-Factor Investigations. She arrives at the orphanage where she had lived before M-Day and, after conversing with her younger self, initiates the chain of events that will eventually lead to her joining X-Factor. Layla accomplishes this by transferring her accumulated knowledge into her younger counterpart's mind. Upon recovering, Layla departs, reflecting on the consequences of her actions.
Return to present Following the disappearance of the
Invisible Woman, it is revealed Layla has been living with Doctor Doom in an advisory capacity for a year, awaiting to cross paths with X-Factor while they search for Susan Richards. During the events of
Second Coming,
Bastion assigns
Bolivar Trask and the
Mutant Response Division to kill every member of X-Factor Investigations. Arriving at Dublin Airport, Layla and
Shatterstar have come to the aid of Theresa Cassidy, who is now going by the codename Banshee. During the confrontation, Layla uses technology acquired from Doom to combat the MRD soldiers and point Monet in the right direction to help turn the tide of the battle. When the demon Bloodbath attacks X-Factor, Jamie is unexpectedly killed. After Jamie is brought back from the dead, Layla states that she knew Jamie would be back and gives into her feelings for him. She proceeds to warm up Jamie from his frozen state by having sex with him. After their tryst, Layla proceeds to tell Jamie about the changes in X-Factor Investigations during his time away. Layla and Jamie elope in Las Vegas, intending to get married, but their honeymoon is cut short when the wedding priest is murdered. ==Powers and abilities==