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Albert Leduc (1902–1990), Canadian ice hockey player •
Alexandre Leduc (born 1984), Canadian politician •
Amand Leduc (1764–1832), French Navy officer •
Amanda Leduc, Canadian writer •
Audrey Leduc (born 1999), Canadian sprinter •
Jos LeDuc (1944–1999), Canadian professional wrestler •
Kyle LeDuc (1981–2023), American racing driver •
Noella Leduc (1933–2014), All-American Girls Professional Baseball League player •
Ozias Leduc (1864–1955), Canadian painter •
Renato Leduc (1897–1986), Mexican poet and journalist •
René Leduc (1898–1968), the designer of the world's first ramjet-powered aircraft •
Richard Leduc (born 1941), French actor •
Simon Le Duc or Leduc (1742–1777), French violinist and composer •
Stéphane Leduc (1853–1939), French biologist •
Timothy LeDuc (born 1990), American pairskater •
Tom LeDuc (1957–1989), American actor and model •
Violette Leduc (1907–1972), French author •
Dave Leduc (born 1991), Canadian professional fighter •
William Gates LeDuc (1823–1917), American soldier, farmer and lawyer ==Places==