During
Juan Andreu Almazán's 1940 presidential campaign, Verdugo Quiroz served as his local campaign manager for the Territory of Baja California Norte. He was helping Andreu Almazán of the
Revolutionary Party of National Unification (PRUN) challenge
Manuel Ávila Camacho of the ruling
Party of the Mexican Revolution (PRM). On the night of the election, Verdugo Quiroz was arrested in Mexicali, along with two other pro-Almazán leaders, for a shooting at the local PRM headquarters which resulted in Eduardo Garza Senande, the local campaign manager for Ávila Camacho, being struck in an artificial leg. After
Baja California was granted statehood that same year, Verdugo Quiroz emerged as a pre-candidate for the
Institutional Revolutionary Party (PRI) nomination for
Governor of Baja California in the , enjoying significant support from the agricultural sector in Mexicali Valley. He was not chosen by the party to move forward. However, the
Acción Cívica Baja Californiana was absorbed by the PRI, with most of Verdugo Quiroz's supporters following him to his new party. In December 1953, Verdugo Quiroz was cited in a newspaper column by journalist Alberto Rosales as one of five local political figures who might seek a nomination to represent the state in the
Senate of the Republic. The PRI eventually selected Verdugo Quiroz and as its candidates. In the special election held on 4 July 1954, Verdugo Quiroz and Cantú were elected as the state's first two Senators. The pair were sworn in as members of the on 7 September after the election results were certified. They both served in the Senate through the end of the in 1958. Verdugo Quiroz served as president of the Public Health Committee, first secretary of the Social Security Committee and the Agricultural and Development Committee, and second secretary of the Administration Committee. He held his first rally the next month, speaking to over 500 farmers in the Mexicali Valley to officially launch his campaign. However, Verdugo Quiroz was not selected by the party. ==References==