Lethenia is an extinct genus of mackerel shark from the Eocene and Oligocene epochs. The type species, L. vanderbroecki, is from the early Oligocene of Belgium. It is considered closely related to Isurolamna and sometimes included within it. It differs in the morphology of its teeth, which are much more gracile than Isurolamna and has larger spacing between its crown and lateral cusps. A recently descrebried species, L. carranzaensis, was found in the Eocene and Oligocene deposites of Chile, originally descrebried as Isurolamna sp. fossil. Some paleontologist thinks that Lethenia can belongs in reality Lamna species, and not a separate genus, what would make Lethenia a junior synonym.