Libby Zion (November 1965 – March 5, 1984) was a freshman at
Bennington College in
Bennington, Vermont. She took a prescribed
MAOI antidepressant,
phenelzine, daily. A hospital autopsy revealed traces of
cocaine, but other later tests showed no traces. She was the daughter of
Sidney Zion, a lawyer who had been a writer for
The New York Times. Her obituary in
The New York Times, written the day after her death, stated that she had been ill with a "flu-like ailment" for the past several days. The article stated that after being admitted to
New York Hospital, she died of
cardiac arrest, the cause of which was not known. Libby Zion had been admitted to the hospital through the emergency room by the resident physician assigned to the ER on the night of March 4. Raymond Sherman, the Zion family physician, agreed with their plan to hydrate and observe her. Zion was assigned to two residents, Luise Weinstein and Gregg Stone, who both evaluated her. Weinstein, a first-year resident physician (also referred to as intern or
PGY-1), and Stone, a PGY-2 resident, were unable to determine the cause of Zion's illness, though Stone tentatively suggested that her condition might be a simple overreaction to a normal illness. After consulting with Dr. Sherman, the two prescribed
pethidine (meperidine) to control the "strange jerking motions" that Zion had been exhibiting when she was admitted. Weinstein and Stone were both responsible for covering dozens of other patients. After evaluating Zion, they left. Luise Weinstein went to cover other patients, and Stone went to sleep in an
on-call room in an adjacent building. Zion, however, did not improve, and continued to become more agitated. After being contacted by nurses by phone, Weinstein ordered
medical restraints be placed on Zion. She also prescribed
haloperidol by phone to control the agitation. Zion finally managed to fall asleep, but by 6:30, her temperature had soared to . Weinstein was once again called, and measures were quickly taken to try to reduce her temperature, but Zion had a
cardiac arrest and could not be resuscitated. Several years later, physicians concluded the combination of phenelzine and the pethidine given to her by Stone and Weinstein contributed to the development of
serotonin syndrome, which led to increased agitation. This led Zion to pull on her
intravenous catheter, causing Weinstein to order physical restraints, which Zion also fought against. By the time she finally fell asleep, her fever had already reached dangerous levels, and she died soon after of cardiac arrest. ==Publicity and trials==