Nanobiotechnology The terms
"nanobiotechnology" and "bionanotechnology" refer to the combination of ideas, techniques, and sciences of biology and nanotechnology. More specifically, nanobiotechnology refers to the application of nanoscale objects for biotechnology, while bionanotechnology refers to the use of biological components in nanotechnology. Being that much of the biological processes in the human body occur at the cellular level, the small size of
nanomaterials allows for them to be used as tools that can easily circulate within the body and directly interact with intercellular and even intracellular environments. In addition, nanomaterials can have physiochemical properties that differ from their bulk form due to their size, allowing for varying chemical reactivities and diffusion effects that can be studied and changed for diversified applications. A common application of nanomedicine is in therapeutic drug delivery, where nanoparticles containing drugs for therapeutic treatment of disease are introduced into the body and act as vessels that deliver the drugs to the targeted area. The nanoparticle vessels, which can be made of organic or synthetic components, can further be functionalized by adjusting their size, shape, surface charge, and surface attachments (proteins, coatings, polymers, etc.). The opportunity for functionalizing nanoparticles in such ways is especially beneficial when targeting areas of the body that have certain physiochemical properties that prevent the intended drug from reaching the targeted area alone; for example, some nanoparticles are able to bypass the
Blood Brain Barrier to deliver therapeutic drugs to the brain. Nanoparticles have recently been used in cancer therapy treatments and vaccines. Magnetic nanorobots have demonstrated capabilities to prevent and treat antimicrobial resistant bacteria. The application of
nanomotor implants have been proposed to achieve thorough disinfection of the dentine.
In vivo imaging is also a key part in nanomedicine, as nanoparticles can be used as
contrast agents for common imaging techniques such as computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET). The ability for nanoparticles to localize and circulate in specific cells, tissues, or organs through their design can provide high contrast that results in higher sensitivity imaging, and thus can be applicable in studying
pharmacokinetics or visual disease diagnosis. == Energy applications ==