Cambage plays at the
centre position in basketball. In 2009, she played in the Under-20 Australian National Championships, and the
ABC suggested she could be the next
Lauren Jackson.
WNBL Cambage played her junior basketball with
Dandenong Rangers, joining their WNBL team for the 2007–08 season. In 2007, she accepted a scholarship to the
Australian Institute of Sport (AIS), and played for the
AIS team, based in
Canberra, in the
Women's National Basketball League (WNBL), for the remainder for the 2007–08 season and the following one In August 2020, Cambage made her return to the WNBL, signing with the
Southside Flyers for the 2020–21 season.
WNBA of the
Minnesota Lynx In March 2011, Cambage expressed a reluctance to play for the
Women's National Basketball Association (
WNBA) team that drafted her, the
Tulsa Shock, stating, "I don't want to play at Tulsa, I've made that clear. They want to make me a franchise player, but I'm not going to the WNBA for that. I'm going there to learn and improve my game. But what can you do?" She played in the
2011 WNBA All-Star Game. After the 2012 Summer Olympics, Cambage was due to head back to the United States to complete the WNBA season with the
Tulsa Shock, but announced on the morning her flight was due to leave, 27 August 2012, that she would not be returning to finish the 2012 season. Her agent released a statement saying she was exhausted after playing for the national team. Cambage returned to play for the Shock for the 2013 season, but did not return to the WNBA for five years after. In February 2018, she signed a multi-year contract with the
Dallas Wings. ===
WCBA=== In June 2012, Cambage signed with
Zheijang Chouzhou basketball club in China, reportedly for a salary of
AUS$400,000, which made her one of the highest-paid female basketballers in the world. Yet in an article in the Australian newspaper
The Age published on 8 March 2019, Cambage reported being poorly compensated and unable to meet her mortgage payments, noting that she had not been paid since September 2018 after an injury prevented her from playing in China. She was quoted as saying: "It's funny, we make all these sacrifices for our nation, but are we getting looked after properly at the end of the day?"
Return to WNBA In February 2018, Cambage signed a multiyear contract with the
Dallas Wings. On 17 July 2018, in a game against the
New York Liberty, Cambage scored a WNBA record 53 points (the mark was later tied by A'ja Wilson). Cambage was voted into the
2018 WNBA All-Star Game, making it her second all-star appearance. Following her 53-point performance, she scored 35 points in a 90–81 victory over the
Washington Mystics, making it the highest two-game point total in league history. By the end of the season, Cambage led the league in scoring and the Wings finished with a 15–19 record as the number-eight seed in the league. In the first-round elimination game, the Wings lost, 101–83, to the
Phoenix Mercury. On 22 January 2019, Cambage requested a trade from the Wings. On 16 May 2019, she was traded to the
Las Vegas Aces. During the 2019 season, Cambage was voted into the
All-Star Game, making it her third all-star appearance. At the end of the season, the Aces finished 21–13 and with the number-four seed, receiving a bye to the second round. In the second-round elimination game, the Aces advanced to the semifinals after defeating the
Chicago Sky, 93–92, off a play by teammate
Dearica Hamby in which she came up with a steal and nailed a desperation three-pointer from half court. In the semifinals, the Aces' playoff run came to an end as they were defeated by the eventual champions, the
Washington Mystics, in four games. On 5 July 2020, the team announced that Cambage would sit out the 2020 WNBA season due to health concerns and pre-existing risk factors surrounding the
COVID-19 pandemic after an evaluation by the team doctor. Without Cambage, the Aces finished the season with an 18–4 record and the number-one seed in the shortened 22-game season; they reached the
2020 WNBA finals, but were swept by the
Seattle Storm. On 23 May 2021, during a game against the Connecticut Sun, opposing coach
Curt Miller lobbied the referee for a foul call on Cambage, while hyperbolically saying that she was "300 pounds". Cambage responded with a post on Instagram, calling Miller a "little white man". Cambage signed with the Los Angeles Sparks on 15 February 2022. During the 2022 season, though, at Cambage's request, she was released on 26 July by the Sparks from her contract. Three weeks later, on 15 August 2022, Cambage announced she was stepping away from the WNBA.
Maccabi Bnot Ashdod (2023) On 3 March 2023, it was announced that Cambage had signed a contract with the Israeli women's basketball club
Maccabi Bnot Ashdod, marking Cambage's first appearance in an Israeli basketball league after playing for teams in Australia, the United States and China.
Sichuan Yuanda (2024–present) In 2024, Cambage returned to the WCBA and signed with Sichuan. In 18 games, she averaged 23.1 points and 11.3 rebounds, helping the team to the WCBA championship. In June 2024, she re-signed with the team for the
2024–2025 season. ==National team career==