Loikaw was the Headquarters of the Political Officer in Charge of the
Karenni States, part of the
Princely States of British Burma, in 1922 during
British rule in Burma. The town was located in the only flat part of the Karenni area. In 1892 it numbered four huts. As an
Agent of the British government he was exercising control over the local Karenni Rulers, being supervised by the Superintendent at
Taunggyi. The headquarters of the
American Baptist Mission to Hill Karens was also located in Loikaw. As with the rest of Karenni State, outsider access to Loikaw has been restricted post-independence, with special permits required to secure entry. Since the 2021 coup, Loikaw has been the scene of intense fighting between the Burmese military and ethnic armed groups opposed to military control, forcing many of the city's residents to flee. On 7 November 2023, the
Karenni National People's Liberation Front,
Karenni Army, and
Karenni Nationalities Defence Force launched a military offensive known as
Operation 1107 against the ruling
State Administration Council junta. An additional offensive, known as
Operation 1111, started on 11 November 2023 with the aim of capturing Loikaw. By 18 December, anti-junta forces were reported to have control of 85% of the city. ==Demographics==