Lopo Vaz de Sampaio was the 6th Governor of Portuguese India from 1526 to 1529. He was also the captain of Vasco da Gama, a famous Portuguese explorer. During 1528–29, Lopo Vaz de Sampaio seized the fort of Mahim from the Gujarat Sultanate, when the King was at war with Nizam-ul-mulk, the emperor of Chaul, a town south of Bombay.