Guerrero died on October 6, 2006, after a long illness. A state funeral was held. Guerrero, the first of the CNMI's elected governors to pass away, was survived by his wife, ten children, and about forty grandchildren and great-grandchildren. The funeral mass were held at the Kristo Rai Church and Nuestra Senora de la Paz Chapel. He was buried at the Mount Carmel Cemetery (Chalan Kanoa Cemetery) in Saipan. Guerrero was married to Matilde Salas Villagomez Deleon Guerrero and had thirteen children, Aida, Joaquin, Margarita, Frances, Gloria, Emiliana, Dolores, Lorenza,
Lorenzo Jr., Magdalena, Raymond, Patricia, and
Edith. == References ==