Los Amigos High School first opened its doors to students in 1968. The first classes of the 1968–1969 academic year were sophomores who had been freshmen at
La Quinta High School and
Santiago High School. New freshmen came from Fitz Intermediate School, as well as Peters Junior High School. There were only two classes of freshmen and sophomores during the school's first academic year. The 1969–1970 academic year saw three classes for freshmen, sophomores, and juniors. The school offered classes from freshmen through seniors in the 1970–1971 academic year. The first graduating class was 1971. The class of 1971 and 1972 wrote both the fight song and the Alma Mater. Although the colors of the school, black and orange were assigned by the district, the Lobo Mascot was picked by the two classes as well. The class of 1972 collected enough money to paint Los Amigos High School and the school mascot, the Lobo (wolf), across the front of the gymnasium, which was overseen by inaugural principal Hal Butler. Conceived at a time when "
open education" was the movement of the day in public education, Los Amigos was constructed in a rather unconventional manner for the warm climate of Southern California. Not only were both of the school's primary classroom buildings - the "L" and "M" buildings - built with interior corridors, all classrooms were built without doors. It would not be until the late 1990s before all classrooms at Los Amigos were provided with doors. Recently the school installed several new classrooms the "A","B","C" and "D" portables to accommodate the increasing number of freshmen each year. The school has now remodeled their "M" and "L" buildings with new modifications to the classrooms. The "M" building has been dubbed the 100 Building and the "L" building has been named the 200 building. Since opening its doors in 1968, Los Amigos has been led by the following principals: Hal Butler, Ken Calkins, George Wilson, Connie Van Luit, Robin Patterson, Vicky Braddock, Amy Avina, and Todd Nirk. ==Academics==